Searchable abstracts of presentations at key conferences in endocrinology

ea0068p2 | Abstracts | UKINETS2019

The role of Thymosin Beta 4 as an autocrine mitogen in neuroendocrine tumours

Beaumont Nicholas , Liang Shuxin , Cuenco Joy , Marotta Davide , Mandair Dalvinder , Balasundaram Ponni , Semkova Mariya , Waugh Mark , Srirajaskanthan Raj , Pereira Stephen , Caplin Martyn , Lu Xiufang , Hsuan Justin

Neuroendocrine tumours (NETs) occur in multiple tissues and vary widely in clinical behaviour. Up to 70% of diagnosed patients have elevated circulating levels of chromogranin A, the only serum marker commonly used in clinical practice. However, its low sensitivity and the identification of confounding factors that compromise specificity have raised the need for additional or alternative markers for disease detection and management. Here we aimed to discover candidate NET mark...